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Publications of interest

As a science-led organisation, Evox is working at the leading edge of exosome therapeutics research and development. Our scholarship manifests itself in peer-reviewed publications and review articles published in leading journals. Below are some recent examples of research published by Evox and its collaborators, as well as articles featuring our pioneering work:

In vivo exosome based therapy for liver inherited metabolic disease: ASL deficiency
Gurung et al., American Society for Cell and Gene Therapy Poster Presentation, 2020

Functional extracellular vesicles aplenty (Nature subscription required)
Zickler et al., Nature Biomedical Engineering, 2020

Exosome redux (Nature subscription required)
Zipkin, M., Nature Biotechnology, 2019

Advances in therapeutic applications of extracellular vesicles
Wiklander et al., Science Translational Medicine, 2019

Optimisation of imaging flow cytometry for the analysis of single extracellular vesicles by using fluorescence-tagged vesicles as biological reference material
Görgens et al., Journal of Extracellular Vesicles, 2019

Systematic methodological evaluation of a multiplex bead-based flow cytometry assay for setection of extracellular vesicle surface signatures
Wiklander et al., Frontiers in Immunology, 2018

Reproducible and scalable purification of extracellular vesicles using combined bind-elute and size exclusion chromatography
Corso et al., Nature Scientific Reports, 2017

Systemic exosomal siRNA delivery reduced alpha-synuclein aggregates in brains of transgenic mice
Cooper et al., Movement Disorders, 2014

Extracellular vesicles: biology and emerging therapeutic opportunities
El Andaloussi et al., Nature, 2013

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
Alvarez-Erviti et al., Nature Biotechnology, 2011